Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967120 | 0.71 | TSHR (0.40) | MEN1USP2KMT2ATDP1POLB | |
| SCHEMBL11548719 | 0.68 | KMT2A (0.50) | MEN1USP2KMT2ATDP1POLB | |
| SCHEMBL2016026 | 0.67 | FAAH (0.31) | TSHRAHR | |
| SCHEMBL3280066 | 0.62 | NPC1 (0.61) | TSHRGAAMAPTRECQLNPC1 | |
| SCHEMBL5544146 | 0.62 | HTT (0.56) | MEN1USP2KMT2ATSHRGAA | |
| SCHEMBL4231163 | 0.60 | MAPT (0.59) | TDP1TSHRGAAMAPTRECQL | |
| SCHEMBL12099730 | 0.60 | TSHR (0.39) | MEN1KMT2APOLBTSHRGAA | |
| SCHEMBL24185552 | 0.58 | CA1 (0.49) | MEN1KMT2APOLBTSHRGAA | |
| SCHEMBL11748979 | 0.58 | CYP1A2 (0.68) | MEN1KMT2APOLBTSHRGAA | |
| SCHEMBL24185323 | 0.57 | NPC1 (0.56) | MEN1KMT2ATDP1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618974-A1 | OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |