Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.63 |
| ▸ | RARA | P10276 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427153 | 0.86 | GCK (0.65) | GCKKCNH2RARARARB | |
| SCHEMBL2660380 | 0.86 | GCK (0.65) | GCKKCNH2RARARARB | |
| SCHEMBL1493779 | 0.84 | GCK (0.66) | GCKKCNH2RARARARB | |
| SCHEMBL1426977 | 0.84 | GCK (0.66) | GCKKCNH2RARARARB | |
| SCHEMBL30960493 | 0.79 | GCK (0.50) | GCKKCNH2RARARARBABL1 | |
| SCHEMBL1427017 | 0.76 | GCK (1.00) | GCKKCNH2RARARARB | |
| SCHEMBL1427220 | 0.76 | GCK (1.00) | GCKKCNH2 | |
| SCHEMBL1426683 | 0.76 | GCK (1.00) | GCKKCNH2 | |
| SCHEMBL10072047 | 0.76 | GCK (0.76) | GCKKCNH2RARARARB | |
| SCHEMBL1042208 | 0.75 | GCK (0.53) | GCKKCNH2RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265703-A | Therapeutic co-crystals of 3- { [5- (azetidin-1-ylcarbonyl) pyrazin-2-yl ] oxy } -5- { [ (1S) -1-methyl-2- (methoxy) ethyl ] oxy) -N- (5-methylpyrazin-2-yl) benzamide | 康杜英国管理有限公司 | 2024-06-28 | — | — | CN | disclosed |