Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17591352 | 0.74 | PDE3B (0.37) | ALDH1A1HSD17B10 | |
| SCHEMBL12037152 | 0.71 | HPGD (0.43) | LRRK2HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14437963 | 0.71 | ALDH1A1 (0.35) | LRRK2KMT2AMEN1ALDH1A1PKM | |
| SCHEMBL17200301 | 0.67 | AXL (0.48) | ALDH1A1HSD17B10 | |
| SCHEMBL9934613 | 0.67 | ALDH1A1 (0.40) | ALDH1A1HSD17B10 | |
| SCHEMBL24469160 | 0.67 | ALDH1A1 (0.35) | ALDH1A1HSD17B10 | |
| SCHEMBL16151425 | 0.67 | ADORA2A (0.36) | ALDH1A1HSD17B10KDM4E | |
| SCHEMBL30278653 | 0.67 | AXL (0.48) | ALDH1A1HSD17B10 | |
| SCHEMBL18239088 | 0.67 | ALDH1A1 (0.32) | ALDH1A1HSD17B10 | |
| SCHEMBL17591346 | 0.67 | ADORA2A (0.34) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |