Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 4/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967474 | 0.84 | SCN9A (0.32) | LRRK2SCN9AABL1 | |
| SCHEMBL30967529 | 0.78 | HRH3 (0.32) | HRH3LRRK2SCN9AHCRTR1HCRTR2 | |
| SCHEMBL30967485 | 0.77 | SCN9A (0.35) | HRH3CYP2D6LRRK2SCN9A | |
| Hydrochloric Acid SCHEMBL30967504 | 0.76 | SCN9A (0.34) | HRH3CYP2D6SCN9A | |
| SCHEMBL30967533 | 0.76 | HRH3 (0.34) | HRH3SCN9A | |
| SCHEMBL30967486 | 0.76 | HRH3 (0.32) | HRH3SCN9A | |
| SCHEMBL30967583 | 0.76 | HRH3 (0.32) | HRH3SCN9A | |
| SCHEMBL30967664 | 0.74 | — | — | |
| SCHEMBL30967631 | 0.71 | SCN9A (0.34) | SCN9A | |
| SCHEMBL19187461 | 0.69 | PARP1 (0.42) | HRH3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |