Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 10/20 | 0.38 |
| ▸ | HTR2A | P28223 | 9/20 | 0.38 |
| ▸ | HTR2B | P41595 | 7/20 | 0.38 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | DCK | P27707 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967565 | 0.93 | SMN1; SMN2 (0.40) | SMN1; SMN2HTR2CHTR2AHTR2BCYBB | |
| SCHEMBL30967452 | 0.87 | MCHR1 (0.40) | SMN1; SMN2CYBBNCF1KDM4EMAPK1 | |
| SCHEMBL12804043 | 0.80 | CYP3A4 (0.50) | SMN1; SMN2KDM4EMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL30967646 | 0.71 | KDM4E (0.44) | SMN1; SMN2CYBBNCF1KDM4EMAPK1 | |
| SCHEMBL30967561 | 0.70 | HSD17B10 (0.40) | SMN1; SMN2KDM4EMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL25323852 | 0.70 | KDM4E (0.68) | SMN1; SMN2KDM4EMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL288073 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPK1HSD17B10ALDH1A1LMNA | |
| SCHEMBL288072 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL106132 | 0.69 | SMN1; SMN2 (0.72) | SMN1; SMN2KDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL30967578 | 0.69 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |