Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967528 | 0.92 | KIFC1 (0.39) | KIFC1MAPK8DRD3MMP13EPHX2 | |
| SCHEMBL30967469 | 0.87 | KIFC1 (0.35) | KIFC1MAPK8MMP13TYK2 | |
| SCHEMBL30967686 | 0.86 | KIFC1 (0.35) | KIFC1MAPK8DRD3MMP13KCNH2 | |
| SCHEMBL30967580 | 0.83 | EPHX2 (0.34) | KIFC1MAPK8EPHX2KCNH2SCN5A | |
| SCHEMBL30967571 | 0.82 | KIFC1 (0.41) | KIFC1MAPK8DRD3MMP13TYK2 | |
| SCHEMBL30967488 | 0.81 | KIFC1 (0.38) | KIFC1MAPK8DRD3MMP13FYN | |
| SCHEMBL30967456 | 0.80 | DRD3 (0.44) | KIFC1DRD3KCNH2 | |
| SCHEMBL30967629 | 0.80 | DRD3 (0.44) | KIFC1DRD3KCNH2 | |
| SCHEMBL30967508 | 0.79 | DYRK1A (0.35) | — | |
| SCHEMBL30967493 | 0.78 | KIFC1 (0.40) | KIFC1MAPK8DRD3MMP13FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |