Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967457 | 0.70 | SYK (0.43) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL30967451 | 0.69 | PARP1 (0.36) | SYKTDP1 | |
| SCHEMBL27619942 | 0.69 | SYK (0.70) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL14497036 | 0.69 | SYK (0.70) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL30269165 | 0.68 | SYK (0.71) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL30489620 | 0.68 | SYK (0.74) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL14497009 | 0.68 | SYK (0.74) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL28668267 | 0.68 | SYK (0.74) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL14497010 | 0.67 | SYK (0.66) | SYKMAPTKLK7KLK5ATM | |
| SCHEMBL975349 | 0.66 | SYK (0.74) | SYKMAPTATMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |