Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 4/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30967484 | 0.87 | GAA (0.34) | MAPTCTSLALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30967543 | 0.84 | SMN1; SMN2 (0.33) | ALDH1A1LMNASMN1; SMN2CTSS | |
| SCHEMBL30967624 | 0.80 | BTK (0.33) | LMNA | |
| SCHEMBL30967546 | 0.78 | DYRK1A (0.36) | SCN9AJAK2 | |
| SCHEMBL30967599 | 0.74 | MDM2 (0.35) | — | |
| SCHEMBL30967508 | 0.71 | DYRK1A (0.35) | SCN9AJAK2 | |
| SCHEMBL28682514 | 0.69 | SYK (0.64) | SYKMAPTCTSLATMCTSS | |
| SCHEMBL30500927 | 0.69 | SYK (0.64) | SYKMAPTCTSLATMCTSS | |
| SCHEMBL30967529 | 0.69 | HRH3 (0.32) | SCN9A | |
| SCHEMBL30967485 | 0.68 | SCN9A (0.35) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615838-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099898-A1 | SUBSTITUTED BI-AND TRICYCLIC HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |