SCHEMBL30967692

SCHEMBL30967692

O=P(Cl)(Cl)Oc1cccc2ncccc12

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
POLB P06746 2/20 0.42
PABPC1 P11940 2/20 0.40
EIF4H Q15056 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
NR3C1 P04150 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HDAC6 Q9UBN7 1/20 0.38
NSD2 O96028 1/20 0.38
FABP5 Q01469 1/20 0.38
SCN9A Q15858 1/20 0.38
CACNA2D1 P54289 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL720268 1.00 KDM4E (0.44) KDM4EMAPTPOLBPABPC1EIF4H
SCHEMBL722425 0.84 KDM4E (0.41) KDM4EMAPTPOLBPABPC1EIF4H
SCHEMBL790313 0.83 MAPT (0.44) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL28062487 0.76 CACNA2D1 (0.47) KDM4EMAPTCACNA2D1
SCHEMBL720108 0.75 MEN1 (0.40) KDM4EMAPTPOLBPABPC1EIF4H
SCHEMBL722399 0.75 KDM4E (0.50) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL29096082 0.74 SYK (0.57) KDM4EMAPTKMT2AL3MBTL1SMN1; SMN2
SCHEMBL28178369 0.74 MAPT (0.54) KDM4EMAPTPOLBMEN1KMT2A
SCHEMBL96953 0.74 SYK (0.57) KDM4EMAPTKMT2AL3MBTL1SMN1; SMN2
SCHEMBL27958848 0.74 KDM4E (0.48) KDM4EMAPTPOLBSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459515-A Preparation method of 2 '-azidoamide-6' -mannoside-phosphate compound 杭州瑞奥生物医药有限公司 2024-08-09 CN disclosed