Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 10/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574766 | 0.86 | HTR1A (0.45) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL8068790 | 0.86 | ALDH1A1 (0.48) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL23412378 | 0.85 | MAPT (0.52) | KDM4EMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8058421 | 0.84 | NCF1 (0.50) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL23412188 | 0.83 | NCF1 (0.51) | KDM4EMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL94786 | 0.81 | KDM4E (0.48) | KDM4EMAPTNR3C1CACNA2D1POLB | |
| SCHEMBL23412437 | 0.81 | NCF1 (0.58) | KDM4EMAPTALDH1A1POLBHTR1A | |
| SCHEMBL9601934 | 0.81 | SYK (0.54) | KDM4EMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28146672 | 0.81 | KDM4E (0.48) | KDM4EMAPTNR3C1CACNA2D1POLB | |
| SCHEMBL23412668 | 0.80 | NCF1 (0.59) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103797024-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-06-01 | — | — | CN | disclosed |
| CN-104918941-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-09-16 | — | — | CN | disclosed |
| CN-103797024-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-05-14 | — | — | CN | disclosed |