Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794577 | 1.00 | MRGPRX4 (0.42) | MRGPRX4CA12CA1CA2CA4 | |
| SCHEMBL1935899 | 0.80 | PPARG (0.44) | MRGPRX4CA12CA1CA2CA4 | |
| SCHEMBL28114618 | 0.78 | CA12 (0.57) | CA12CA1CA2CA4CA6 | |
| SCHEMBL27423552 | 0.76 | SMN1; SMN2 (0.56) | TSHRALDH1A1RAB9AHTTKDM4E | |
| SCHEMBL2046361 | 0.74 | HTT (0.44) | MRGPRX4CA12CA1CA2CA4 | |
| SCHEMBL31721229 | 0.74 | CA12 (0.45) | MRGPRX4CA12CA1CA2CA4 | |
| SCHEMBL5319903 | 0.72 | RAF1 (0.42) | KMOALDH1A1RAB9AHTTMEN1 | |
| SCHEMBL30309762 | 0.72 | KDR (0.47) | MRGPRX4TTRMAP4K2MAP3K7 | |
| SCHEMBL26602042 | 0.72 | KDR (0.47) | MRGPRX4TTRMAP4K2MAP3K7 | |
| SCHEMBL15490439 | 0.71 | SMN1; SMN2 (0.41) | TSHRALDH1A1RAB9AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50030-E1 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-07-02 | — | — | US | disclosed |