Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237392 | 1.00 | NPSR1 (0.41) | NPSR1CYP4F2CYP4A11GAAALOX5 | |
| SCHEMBL29237237 | 0.89 | CYP4F2 (0.38) | NPSR1CYP4F2CYP4A11GAAALOX5 | |
| SCHEMBL29237466 | 0.84 | NPSR1 (0.40) | NPSR1CYP4F2CYP4A11GAAALOX5 | |
| SCHEMBL31108605 | 0.84 | NPSR1 (0.40) | NPSR1CYP4F2CYP4A11GAAALOX5 | |
| SCHEMBL29237551 | 0.81 | MAPT (0.42) | NPSR1CYP4F2CYP4A11TDP1CHRM5 | |
| SCHEMBL30217241 | 0.81 | MAPT (0.42) | NPSR1CYP4F2CYP4A11TDP1CHRM5 | |
| SCHEMBL30967833 | 0.77 | BACE1 (0.52) | NPSR1GAAALOX5ALDH1A1OPRM1 | |
| SCHEMBL29237211 | 0.77 | BACE1 (0.52) | NPSR1GAAALOX5ALDH1A1OPRM1 | |
| SCHEMBL30217340 | 0.77 | BACE1 (0.52) | NPSR1GAAALOX5ALDH1A1OPRM1 | |
| SCHEMBL29237214 | 0.77 | BACE1 (0.52) | NPSR1GAAALOX5ALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |