Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237551 | 1.00 | MAPT (0.42) | MAPTCYP4F2CYP4A11CHRM5CHRM1 | |
| SCHEMBL30217338 | 0.88 | CYP4F2 (0.39) | MAPTCYP4F2CYP4A11CHRM5CHRM1 | |
| SCHEMBL29237682 | 0.88 | CYP4F2 (0.39) | MAPTCYP4F2CYP4A11CHRM5CHRM1 | |
| SCHEMBL30967845 | 0.81 | NPSR1 (0.41) | MAPTCYP4F2CYP4A11CHRM5CHRM1 | |
| SCHEMBL29237392 | 0.81 | NPSR1 (0.41) | MAPTCYP4F2CYP4A11CHRM5CHRM1 | |
| SCHEMBL30217226 | 0.79 | OPRM1 (0.59) | CHRM5CHRM1CHRM3OPRM1OPRD1 | |
| SCHEMBL29237501 | 0.79 | OPRM1 (0.41) | CYP4F2CYP4A11CHRM5CHRM1CHRM3 | |
| SCHEMBL4425984 | 0.75 | CYP4F2 (0.64) | CYP4F2CYP4A11TDP1SYK | |
| SCHEMBL31108605 | 0.74 | NPSR1 (0.40) | MAPTCYP4F2CYP4A11CHRM5CHRM1 | |
| SCHEMBL29237466 | 0.74 | NPSR1 (0.40) | MAPTCYP4F2CYP4A11CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023034992-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |