Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217084 | 1.00 | SIRT2 (0.44) | SIRT2PDE4DBRD4PTPN1CYP4F2 | |
| SCHEMBL30216977 | 0.81 | SIRT2 (0.43) | SIRT2PDE4DBRD4PTPN1CYP4F2 | |
| SCHEMBL29237217 | 0.79 | BRD4 (0.42) | SIRT2PDE4DBRD4PTPN1CYP4F2 | |
| SCHEMBL5748661 | 0.74 | SIRT2 (0.51) | SIRT2BRD4PTPN1CYP4F2CYP4A11 | |
| SCHEMBL3627247 | 0.73 | SLC7A5 (0.51) | SIRT2BRD4PTPN1CYP4F2CYP4A11 | |
| SCHEMBL27399582 | 0.73 | CYP4F2 (0.54) | SIRT2BRD4CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL1107166 | 0.72 | SIRT2 (0.52) | SIRT2BRD4CYP4F2CYP4A11KDM4E | |
| SCHEMBL1124591 | 0.72 | SPR (0.57) | SIRT2CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL30655576 | 0.72 | SPR (0.57) | SIRT2CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL1410879 | 0.72 | SIRT2 (0.52) | SIRT2BRD4PTPN1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |