Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CTSE | P14091 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968019 | 0.84 | CHRM2 (0.32) | CHRM2CHRM1CHRM3 | |
| SCHEMBL30967970 | 0.84 | CHRM2 (0.32) | CHRM2CHRM1CHRM3 | |
| SCHEMBL30968061 | 0.82 | CHRM2 (0.37) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL6255532 | 0.78 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL30968111 | 0.78 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL25091833 | 0.78 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL30204761 | 0.78 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL30968027 | 0.77 | DDB1 (0.36) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL30968017 | 0.77 | CHRM2 (0.36) | CHRM2CHRM1CHRM3KDM4EMAPT | |
| SCHEMBL23264965 | 0.73 | CHRM2 (0.41) | CHRM2CHRM1CHRM3DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |