Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | CASP3 | P42574 | 2/20 | 1.00 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 1.00 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 1.00 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | MIF | P14174 | 5/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.72 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547900 | 1.00 | MAPT (1.00) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8547897 | 1.00 | MAPT (1.00) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL25609318 | 1.00 | MAPT (1.00) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8548470 | 0.90 | MAPT (0.81) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8548473 | 0.90 | MAPT (0.81) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8543845 | 0.89 | MAPT (0.80) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL30967941 | 0.88 | MAPT (1.00) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL20526853 | 0.88 | MAPT (1.00) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL14802067 | 0.88 | MAPT (1.00) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL27337921 | 0.88 | MAPT (1.00) | MAPTALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12023348-B2 | EGR1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions | The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center (IL) | 2024-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12023348-B2 | EGR1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions | TOE1, ATF1, ELF3 | MAPT 4412/4885ALDH1A1 1844/4885LMNA 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.