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Sugi Predict / Targets / ELF3

ELF3

ETS-related transcription factor Elf-3 (E74-l · P78545 · ELF3 on Sugi Atlas →

303 patent compounds predicted against ELF3, 126 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL19365750 SCHEMBL19365750 0.49 4/20
SCHEMBL12837315 SCHEMBL12837315 0.48 4/20
SCHEMBL13449584 SCHEMBL13449584 0.48 4/20
SCHEMBL19669056 SCHEMBL19669056 0.48 4/20
SCHEMBL878574 SCHEMBL878574 0.46 4/20
SCHEMBL20276070 SCHEMBL20276070 0.45 4/20
SCHEMBL14340272 SCHEMBL14340272 0.43 4/20
SCHEMBL13971295 SCHEMBL13971295 0.58 3/20
SCHEMBL23941161 SCHEMBL23941161 0.49 3/20
SCHEMBL14038088 SCHEMBL14038088 0.49 3/20
SCHEMBL15216676 SCHEMBL15216676 0.46 3/20
SCHEMBL15216663 SCHEMBL15216663 0.45 3/20
SCHEMBL18720047 SCHEMBL18720047 0.45 3/20
SCHEMBL22458006 SCHEMBL22458006 0.45 3/20
SCHEMBL23407864 SCHEMBL23407864 0.44 3/20
SCHEMBL18459799 SCHEMBL18459799 0.42 3/20
SCHEMBL22328142 SCHEMBL22328142 0.40 3/20
SCHEMBL22328123 SCHEMBL22328123 0.40 3/20
SCHEMBL22328137 SCHEMBL22328137 0.38 3/20
SCHEMBL12185010 SCHEMBL12185010 0.60 2/20

Clinical trials — most relevant to ELF3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Chronic Effects of Estrogen in Microcirculation PHASE4COMPLETED
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room PHASE2/PHASE3COMPLETED
A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal Women With Early Stage Breast Hormone Receptor Positive (HR+) Human Epidermal Receptor 2 Negative (HER2-) Breast Cancer. PHASE2UNKNOWN
A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer PHASE2UNKNOWN
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL PHASE1/PHASE2RECRUITING
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies PHASE1RECRUITING
Decitabine, Vaccine Therapy, and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer PHASE1COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
EKLF Gene Expression in β-thalassemia nanNOT_YET_RECRUITING
Evaluation of the Predictive Effect of Inflammatory Markers in MI Patients nanUNKNOWN
Esophageal String Test in Eosinophilic Esophagitis nanACTIVE_NOT_RECRUITING
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Immune Interactions in Severe Asthma nanCOMPLETED
Sorting and Expression Profiling of Airway Cells From Humans (The SEARCH Study) nanCOMPLETED
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics nanCOMPLETED
Card14gene (rs34367357 ) Polymorphism in Egyptian Psoriatic and Psoriatic Arthritis Patient nanRECRUITING
Long Non-coding RNAs and Their Role on Epigenome as Diagnostic Markers in Childhood Acute Lymphoblastic Leukemia of T Cells. nanUNKNOWN
Novel Biophotonics Methodology for Colon Cancer Screening nanCOMPLETED
FoxO3a and PU.1 in Acute Lymphoblastic Leukemia nanUNKNOWN
EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors nanUNKNOWN
MMP Polymorphisms and Acute Coronary Syndromes nanCOMPLETED
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea nanRECRUITING
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia nanUNKNOWN
A Study of Serum Protein Profiling in Patients With Non-Small Cell Lung Cancer Treated With Gefitinib or Erlotinib nanCOMPLETED
Markers for Predicting Risk of Breast Cancer in Women of Different Races nanWITHDRAWN
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN
Selinexor (Nexpovio®) (SVd) in Patients With Relapsed or Refractory Multiple Myeloma nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a ELF3 binder may also engage these)

ProteinNameSimilarity
Q4V7E1 — 1.000 Q4V7E1 →
Q3UPW2 — 1.000 Q3UPW2 →
P18756 — 0.998 P18756 →
Q62661 — 0.996 Q62661 →
MAP3K13 Mitogen-activated protein kinase kinase kinase 13 0.996 landscape →
P46200 — 0.996 P46200 →
Q2PFD7 — 0.995 Q2PFD7 →
Q28F43 — 0.995 Q28F43 →
P06536 — 0.995 P06536 →
Q92539 — 0.995 Q92539 →
P49844 — 0.995 P49844 →
P06537 — 0.995 P06537 →
Q5R7I3 — 0.995 Q5R7I3 →
F1QDF8 — 0.995 F1QDF8 →
Q99PI5 — 0.994 Q99PI5 →
Q90655 — 0.994 Q90655 →
Q499D0 — 0.994 Q499D0 →
O95343 — 0.994 O95343 →
P70284 — 0.994 P70284 →
Q5WM45 — 0.994 Q5WM45 →
A2A3K4 — 0.994 A2A3K4 →
A7MBB4 — 0.994 A7MBB4 →
Q8AYI2 — 0.994 Q8AYI2 →
P10157 — 0.994 P10157 →
Q5TKR9 — 0.994 Q5TKR9 →
O43310 — 0.994 O43310 →
O95238 — 0.994 O95238 →
Q9N1U3 — 0.993 Q9N1U3 →
P10244 — 0.993 P10244 →
Q9FY74 — 0.993 Q9FY74 →