Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26759053 | 0.95 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL29851796 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL30968058 | 0.87 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL2125576 | 0.83 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL25328629 | 0.82 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL16391852 | 0.82 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL30977195 | 0.82 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL25257754 | 0.82 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL30977192 | 0.82 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL30968027 | 0.81 | DDB1 (0.36) | CHRM2CHRM1CHRM3DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |