Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968058 | 0.96 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL26366228 | 0.86 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL25216428 | 0.86 | CHRM2 (0.38) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL26759053 | 0.86 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL2125576 | 0.86 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL16391852 | 0.84 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL25328466 | 0.84 | CHRM2 (0.36) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL22370300 | 0.84 | CHRM2 (0.41) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL16391851 | 0.82 | CHRM2 (0.37) | CHRM2CHRM1CHRM3HPGDPREP | |
| SCHEMBL30968002 | 0.82 | CHRM2 (0.39) | CHRM2CHRM1CHRM3HPGDPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365572-A1 | HYDROXYLBENZYL AZABICYCLO[2.2.1]HEPTAN-1-ANE DRIVATIVES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2023-11-16 | — | — | US | disclosed |
| US-20230365572-A1 | HYDROXYLBENZYL AZABICYCLO[2.2.1]HEPTAN-1-ANE DRIVATIVES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2023-11-16 | — | — | US | disclosed |
| US-20230365572-A1 | HYDROXYLBENZYL AZABICYCLO[2.2.1]HEPTAN-1-ANE DRIVATIVES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2023-11-16 | — | — | US | disclosed |
| EP-4217359-A1 | HYDROXYLBENZYL AZABICYCLO[2.2.1]HEPTAN-1-ANE DRIVATIVES AND MEDICAL USES THEREOF | Atrogi AB (SE) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022063889-A1 | HYDROXYLBENZYL AZABICYCLO[2.2.1]HEPTAN-1-ANE DRIVATIVES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2022-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365572-A1 | HYDROXYLBENZYL AZABICYCLO[2.2.1]HEPTAN-1-ANE DRIVATIVES AND MEDICAL USES THEREOF | CYP1B1, CYP11B1, CYP11B2 | CHRM2 1554/4885CHRM1 748/4885CHRM3 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.