Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333421 | 1.00 | ESR1 (0.38) | ESR1ELANECTDSP1LMNAALDH1A1 | |
| SCHEMBL2535846 | 0.84 | ESR1 (0.48) | ESR1ELANECTDSP1LMNAALDH1A1 | |
| SCHEMBL13777997 | 0.79 | ELANE (0.39) | ESR1ELANECTDSP1LMNAALDH1A1 | |
| SCHEMBL20659863 | 0.78 | ELANE (0.40) | ESR1ELANECTDSP1LMNAALDH1A1 | |
| SCHEMBL1921459 | 0.78 | ESR1 (0.39) | ESR1ELANECTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13764543 | 0.76 | ELANE (0.37) | ESR1ELANECTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29808329 | 0.76 | ELANE (0.37) | ESR1ELANECTDSP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2368765 | 0.75 | ALDH1A1 (0.60) | ESR1LMNAALDH1A1NPC1HPGD | |
| SCHEMBL5127935 | 0.74 | PRKCI (0.51) | LMNAALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL5121836 | 0.73 | NPC1 (0.68) | LMNAALDH1A1NPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |