SCHEMBL30968230

SCHEMBL30968230

N#Cc1cc(N2CCC(C(=O)N3N=CCC3c3ccccc3)C3(CC3)C2)ncn1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22638933 1.00 RIPK1 (0.58) RIPK1
SCHEMBL22644569 0.89 RIPK1 (0.74) RIPK1
SCHEMBL24350157 0.87 RIPK1 (0.52) RIPK1
SCHEMBL22638799 0.87 RIPK1 (0.63) RIPK1
SCHEMBL22644593 0.87 RIPK1 (0.63) RIPK1
SCHEMBL30968269 0.87 RIPK1 (0.63) RIPK1
SCHEMBL22644588 0.87 RIPK1 (0.63) RIPK1
SCHEMBL22644592 0.87 RIPK1 (0.63) RIPK1
SCHEMBL22644591 0.87 RIPK1 (0.63) RIPK1
SCHEMBL22638867 0.86 RIPK1 (0.51) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113767092-B Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine 劲方医药科技(上海)有限公司 2024-07-16 CN disclosed