Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 10/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22638922 | 1.00 | RIPK1 (0.58) | RIPK1GPR119NTRK1BRD4DPP4 | |
| SCHEMBL20166338 | 0.88 | RIPK1 (0.75) | RIPK1GPR119CHRM4 | |
| SCHEMBL20166335 | 0.88 | RIPK1 (0.75) | RIPK1GPR119CHRM4 | |
| SCHEMBL22638829 | 0.86 | RIPK1 (0.41) | RIPK1NTRK1CHRM4 | |
| SCHEMBL29730092 | 0.86 | RIPK1 (0.41) | RIPK1NTRK1CHRM4 | |
| SCHEMBL24350362 | 0.86 | RIPK1 (0.77) | RIPK1GPR119 | |
| SCHEMBL22638983 | 0.86 | RIPK1 (0.77) | RIPK1GPR119 | |
| SCHEMBL22638990 | 0.86 | RIPK1 (0.77) | RIPK1GPR119 | |
| SCHEMBL22638982 | 0.86 | RIPK1 (0.77) | RIPK1GPR119 | |
| SCHEMBL22638984 | 0.86 | RIPK1 (0.77) | RIPK1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767092-B | Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine | 劲方医药科技(上海)有限公司 | 2024-07-16 | — | — | CN | disclosed |