SCHEMBL30968248

SCHEMBL30968248

O=C(C1CCNC2(CC2)C1)N1N=CCC1c1cncc(F)c1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22638970 1.00 RIPK1 (0.43) RIPK1
SCHEMBL22638925 0.90 RIPK1 (0.52) RIPK1
Trifluoroacetic Acid SCHEMBL22638822 0.85 RIPK1 (0.48) RIPK1
SCHEMBL20166527 0.84 RIPK1 (0.51) RIPK1
SCHEMBL20165980 0.84 RIPK1 (0.51) RIPK1
SCHEMBL18248379 0.80 RIPK1 (0.63) RIPK1
SCHEMBL22638890 0.79 RIPK1 (0.34) RIPK1
SCHEMBL22638921 0.76 RIPK1 (0.44) RIPK1
SCHEMBL18248268 0.75 RIPK1 (0.61) RIPK1
SCHEMBL18248271 0.75 RIPK1 (0.61) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113767092-B Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine 劲方医药科技(上海)有限公司 2024-07-16 CN disclosed