Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.56 |
| ▸ | JAK2 | O60674 | 8/20 | 0.36 |
| ▸ | JAK1 | P23458 | 8/20 | 0.36 |
| ▸ | JAK3 | P52333 | 8/20 | 0.36 |
| ▸ | TYK2 | P29597 | 7/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22638884 | 1.00 | RIPK1 (0.56) | RIPK1JAK2JAK1JAK3TYK2 | |
| SCHEMBL24351048 | 0.89 | RIPK1 (0.51) | RIPK1JAK2JAK1JAK3TYK2 | |
| SCHEMBL22638999 | 0.87 | RIPK1 (0.40) | RIPK1JAK2JAK1JAK3TYK2 | |
| SCHEMBL22644569 | 0.87 | RIPK1 (0.74) | RIPK1JAK2JAK1JAK3TYK2 | |
| SCHEMBL24350610 | 0.87 | RIPK1 (0.40) | RIPK1JAK2JAK1JAK3TYK2 | |
| SCHEMBL20166335 | 0.86 | RIPK1 (0.75) | RIPK1GPR119 | |
| SCHEMBL20166338 | 0.86 | RIPK1 (0.75) | RIPK1GPR119 | |
| SCHEMBL22644593 | 0.85 | RIPK1 (0.63) | RIPK1JAK2JAK1JAK3TYK2 | |
| SCHEMBL22644591 | 0.85 | RIPK1 (0.63) | RIPK1JAK2JAK1JAK3TYK2 | |
| SCHEMBL22644592 | 0.85 | RIPK1 (0.63) | RIPK1JAK2JAK1JAK3TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767092-B | Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine | 劲方医药科技(上海)有限公司 | 2024-07-16 | — | — | CN | disclosed |