Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30968466 | 0.87 | PARP1 (0.44) | PARP1HTR2CDPP4SMN1; SMN2NPC1 | |
| SCHEMBL30968423 | 0.84 | PARP1 (0.48) | PARP1HTR2CSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30968480 | 0.83 | PARP1 (0.48) | PARP1HTR2CSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30968543 | 0.79 | PARP1 (0.48) | PARP1HTR2CSMN1; SMN2NPC1RAB9A | |
| SCHEMBL28567927 | 0.79 | SMN1; SMN2 (0.42) | DPP4SMN1; SMN2NPC1RAB9ADPP7 | |
| SCHEMBL30968414 | 0.76 | PARP1 (0.40) | PARP1HTR2CPREPNPSR1ACE2 | |
| SCHEMBL20722816 | 0.76 | SMN1; SMN2 (0.47) | HTR2CDPP4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21685804 | 0.76 | SMN1; SMN2 (0.47) | HTR2CDPP4SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2706679 | 0.75 | HTR2C (0.52) | PARP1HTR2CSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30968411 | 0.74 | PARP1 (0.45) | PARP1HTR2CPREPNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |