Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20722634 | 0.80 | SMN1; SMN2 (0.39) | HTR2CALDH1A1NPSR1SIGMAR1TMEM97 | |
| SCHEMBL30968423 | 0.78 | PARP1 (0.48) | PARP1HTR2CNPSR1SIGMAR1TMEM97 | |
| SCHEMBL30968480 | 0.77 | PARP1 (0.48) | PARP1HTR2CNPSR1PREPSIGMAR1 | |
| SCHEMBL30968415 | 0.76 | PARP1 (0.42) | PARP1HTR2CNPSR1PREPACE2 | |
| SCHEMBL30968466 | 0.76 | PARP1 (0.44) | PARP1HTR2CACE2 | |
| SCHEMBL30968543 | 0.73 | PARP1 (0.48) | PARP1HTR2CNPSR1SIGMAR1TMEM97 | |
| SCHEMBL30968411 | 0.70 | PARP1 (0.45) | PARP1HTR2CALDH1A1NPSR1PREP | |
| SCHEMBL2706679 | 0.69 | HTR2C (0.52) | PARP1HTR2CNPSR1PREPSIGMAR1 | |
| SCHEMBL30499783 | 0.67 | PREP (0.42) | PARP1HTR2CPREPAADATSIGMAR1 | |
| SCHEMBL21129022 | 0.67 | ALDH1A1 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |