Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MC5R | P33032 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28562416 | 0.87 | PARP1 (0.43) | PARP1GPR119MEN1KMT2AKDM4E | |
| SCHEMBL30968455 | 0.79 | CA1 (0.42) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28914274 | 0.78 | HDAC6 (0.40) | GPR119DPP4KDM4EMAPTTHRB | |
| SCHEMBL30968505 | 0.77 | PARP1 (0.38) | PARP1GPR119KDM4EMAPTTHRB | |
| SCHEMBL30968546 | 0.76 | PARP1 (0.38) | PARP1GPR119DPP4KDM4EMAPT | |
| SCHEMBL30059936 | 0.74 | KIT (0.42) | GPR119DPP4KDM4EMAPTTHRB | |
| SCHEMBL20723028 | 0.74 | KIT (0.42) | GPR119DPP4KDM4EMAPTTHRB | |
| SCHEMBL20732039 | 0.74 | KIT (0.42) | GPR119DPP4KDM4EMAPTTHRB | |
| SCHEMBL29085915 | 0.72 | PARP1 (0.39) | PARP1GPR119DPP4MEN1KMT2A | |
| SCHEMBL3245906 | 0.70 | PARP1 (0.39) | PARP1GPR119MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |