Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844211 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL20722419 | 0.87 | LIMK1 (0.51) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL30968434 | 0.87 | LIMK1 (0.51) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL8558549 | 0.84 | IKBKB (0.71) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL31221733 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7050857 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL22957480 | 0.81 | MAPT (0.57) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL22957572 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL22957483 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL22957481 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |