Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.71 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707339 | 0.86 | KDM4E (0.70) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL3494383 | 0.86 | KDM4E (0.70) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL31221733 | 0.84 | KDM4E (0.59) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL30968442 | 0.84 | KDM4E (0.59) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7844211 | 0.84 | KDM4E (0.59) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7050857 | 0.84 | KDM4E (0.59) | MAPTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL4126822 | 0.84 | IKBKB (0.52) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL11102626 | 0.83 | IKBKB (0.64) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL12562427 | 0.83 | LIMK1 (0.77) | IKBKBLIMK1MAPTNPC1RAB9A | |
| SCHEMBL19212039 | 0.83 | LIMK1 (0.77) | IKBKBLIMK1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827857-A | BACTERICIDES AND MICROBIOCIDES; GRAMPOSITIVE BACTERIA, HEMOPHILUS INFLUENZA, ANAEROBIC MICROORGANISMS AND MYCOBACTERIA; LOW TOXICITY | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-27 | — | — | US | disclosed |