Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30060095 | 0.76 | GPR183 (0.38) | RORCNR1H2 | |
| SCHEMBL20731532 | 0.76 | GPR183 (0.38) | RORCNR1H2 | |
| SCHEMBL30059985 | 0.74 | PDK2 (0.37) | DDB1CRBNNR1H2 | |
| SCHEMBL20723048 | 0.74 | PDK2 (0.37) | DDB1CRBNNR1H2 | |
| SCHEMBL20723043 | 0.74 | PDK2 (0.37) | DDB1CRBNNR1H2 | |
| SCHEMBL30968555 | 0.74 | KDM1A (0.31) | DDB1CRBN | |
| SCHEMBL20731008 | 0.68 | MAPT (0.48) | — | |
| SCHEMBL30061346 | 0.68 | MAPT (0.48) | — | |
| SCHEMBL20722608 | 0.68 | MAPT (0.48) | — | |
| SCHEMBL20722615 | 0.67 | ABHD6 (0.43) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |