SCHEMBL30968702

SCHEMBL30968702

O=C1CCC=C/C1=C\c1ccccc1-c1cccs1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTK P29376 1/20 0.36
CDK5 Q00535 1/20 0.36
MST1R Q04912 1/20 0.36
DYRK1A Q13627 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
MAOB P27338 2/20 0.35
EGFR P00533 1/20 0.35
RET P07949 1/20 0.35
KDR P35968 1/20 0.35
CTRC Q99895 1/20 0.35
MAPT P10636 4/20 0.34
PKM P14618 2/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
HPGD P15428 3/20 0.33
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 3/20 0.33
HTT P42858 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29936581 1.00 LTK (0.36) LTKCDK5MST1RDYRK1ACLK4
SCHEMBL29281742 1.00 LTK (0.36) LTKCDK5MST1RDYRK1ACLK4
SCHEMBL3438265 0.74 ALDH1A1 (0.44) LTKCDK5MST1RDYRK1ACLK4
SCHEMBL3438268 0.74 ALDH1A1 (0.44) LTKCDK5MST1RDYRK1ACLK4
SCHEMBL30968703 0.74 BRD4 (0.36) MAOBMAPTNFKB1NFKB2RELA
SCHEMBL29281745 0.74 BRD4 (0.36) MAOBMAPTNFKB1NFKB2RELA
SCHEMBL29936763 0.74 BRD4 (0.36) MAOBMAPTNFKB1NFKB2RELA
SCHEMBL28869856 0.69 ALDH1A1 (0.46) MAOBMAPTNFKB1NFKB2RELA
SCHEMBL29281743 0.69 ALDH1A1 (0.46) MAOBMAPTNFKB1NFKB2RELA
SCHEMBL31456556 0.68 ERN1 (0.49) LTKCDK5MST1RDYRK1ACLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115093315-B Synthesis method of 2-benzylidene-3-cyclohexenone compound 云南民族大学 2024-04-26 CN disclosed