Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565466 | 0.85 | ESR2 (0.50) | SMN1; SMN2HIF1AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL27365154 | 0.81 | ESR2 (0.47) | SMN1; SMN2HIF1AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL18411313 | 0.81 | ESR2 (0.47) | SMN1; SMN2HIF1AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL31663516 | 0.81 | ESR2 (0.47) | SMN1; SMN2HIF1AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL18411452 | 0.80 | TSHR (0.46) | SMN1; SMN2HIF1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1034013 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10ALOX15MEN1 | |
| SCHEMBL30359283 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2HIF1AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL18411431 | 0.77 | ESR2 (0.50) | SMN1; SMN2HIF1AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL769515 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2HIF1AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL16984845 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251380-A | Spiro- (indan-fluorene) compounds and their use in organic electronic devices | 多蒂肯独家合成控股公司 | 2024-06-25 | — | — | CN | disclosed |