Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.59 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27386954 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL515288 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3485988 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3099780 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3099789 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL515289 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3096915 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3114101 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3110817 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3100572 | 1.00 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8535689-B2 | Identification of bacterial autoinducer and use in treating bacterial pathogenicity | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-09-17 | — | — | US | claimed |
| US-20100273890-A1 | IDENTIFICATION OF BACTERIAL AUTOINDUCER AND USE IN TREATING BACTERIAL PATHOGENICITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-10-28 | — | — | US | claimed |
| WO-2009088402-A2 | IDENTIFICATION OF BACTERIAL AUTOINDUCER AND USE IN TREATING BACTERIAL PATHOGENICITY | PRINCETON UNIVERSITY (US) | 2009-07-16 | — | — | WO | claimed |
| US-8535689-B2 | Identification of bacterial autoinducer and use in treating bacterial pathogenicity | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-09-17 | — | — | US | disclosed |
| US-20100273890-A1 | IDENTIFICATION OF BACTERIAL AUTOINDUCER AND USE IN TREATING BACTERIAL PATHOGENICITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-10-28 | — | — | US | disclosed |
| WO-2009088402-A2 | IDENTIFICATION OF BACTERIAL AUTOINDUCER AND USE IN TREATING BACTERIAL PATHOGENICITY | PRINCETON UNIVERSITY (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100273890-A1 | IDENTIFICATION OF BACTERIAL AUTOINDUCER AND USE IN TREATING BACTERIAL PATHOGENICITY | TCP1, CTBP2, HCFC1 | CES2 1469/4885CES1 638/4885ALDH1A1 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.