SCHEMBL30969486

SCHEMBL30969486

Clc1cnc2cc3ccc(Cl)nc3cc2c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 4/20 0.41
PDGFRA P16234 4/20 0.41
ALDH1A1 P00352 1/20 0.37
NR4A2 P43354 1/20 0.36
MET P08581 1/20 0.35
NPC1 O15118 1/20 0.34
ESR2 Q92731 1/20 0.33
BACE1 P56817 1/20 0.33
NOS1 P29475 2/20 0.32
DYRK1A Q13627 1/20 0.32
OGA O60502 1/20 0.32
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
APEX1 P27695 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDR P35968 1/20 0.31
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29237023 1.00 PDGFRB (0.41) PDGFRBPDGFRAALDH1A1NR4A2MET
SCHEMBL30702581 0.79 PDGFRB (0.59) PDGFRBPDGFRAALDH1A1NR4A2NOS1
SCHEMBL7157574 0.79 PDGFRB (0.59) PDGFRBPDGFRAALDH1A1NR4A2NOS1
SCHEMBL29237025 0.78 PDGFRB (0.46) PDGFRBPDGFRAALDH1A1NR4A2MET
SCHEMBL30969480 0.78 PDGFRB (0.46) PDGFRBPDGFRAALDH1A1NR4A2MET
SCHEMBL15551629 0.78 ALDH1A1 (0.45) PDGFRBPDGFRAALDH1A1NR4A2MET
SCHEMBL18554573 0.74 ESR2 (0.59) PDGFRBPDGFRAALDH1A1NR4A2ESR2
SCHEMBL14908778 0.74 HTT (0.54) PDGFRBPDGFRAALDH1A1NR4A2NPC1
SCHEMBL4541479 0.74 HTT (0.50) PDGFRBPDGFRANR4A2METNPC1
SCHEMBL8268977 0.74 ALDH1A1 (0.50) PDGFRBPDGFRAALDH1A1METBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117942786-A Preparation method of nanofiltration membrane and nanofiltration membrane prepared by same 沃顿科技股份有限公司 2024-04-30 CN disclosed