Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.77 |
| ▸ | CRHBP | P24387 | 1/20 | 0.77 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | ALPI | P09923 | 1/20 | 0.55 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096975 | 1.00 | MAPT (0.77) | MAPTRAB9AMEN1KMT2APSMD14 | |
| SCHEMBL16810263 | 0.88 | MAPT (0.73) | MAPTRAB9AMEN1KMT2APSMD14 | |
| SCHEMBL5597968 | 0.85 | MAPT (0.74) | MAPTRAB9AMEN1KMT2APSMD14 | |
| SCHEMBL2053346 | 0.85 | MAPT (0.79) | MAPTRAB9AMEN1KMT2APSMD14 | |
| SCHEMBL979280 | 0.85 | MAPT (0.79) | MAPTRAB9AMEN1KMT2APSMD14 | |
| SCHEMBL15155058 | 0.84 | MAPT (0.72) | MAPTRAB9AMEN1KMT2APSMD14 | |
| SCHEMBL15155060 | 0.84 | MAPT (0.72) | MAPTRAB9AMEN1KMT2APSMD14 | |
| SCHEMBL13721173 | 0.84 | MAPT (1.00) | MAPTRAB9AMEN1KMT2APSMD14 | |
| SCHEMBL18906024 | 0.83 | MAPT (0.70) | MAPTRAB9AMEN1KMT2APSMD14 | |
| SCHEMBL1321557 | 0.83 | MAPT (0.75) | MAPTRAB9AMEN1KMT2APSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803800-B2 | Histone deacetylases inhibitors | DAC S.R.L. (IT) | 2010-09-28 | — | — | US | disclosed |
| US-20080096889-A1 | Histone Deacetylases Inhibitors | GENEXTRA S.P.A. (IT) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096889-A1 | Histone Deacetylases Inhibitors | HDAC1, HDAC3, HDAC11 | MAPT 3192/4885RAB9A 2918/4885MEN1 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.