Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20474213 | 0.85 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL20439669 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL672281 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL672283 | 0.84 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL29110172 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTKMT2AHPGD | |
| SCHEMBL2486592 | 0.75 | KDM4E (1.00) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL30259471 | 0.75 | KDM4E (1.00) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL2486594 | 0.75 | KDM4E (1.00) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL30970392 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL19918087 | 0.74 | CYP3A4 (0.50) | ALDH1A1KDM4EPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626870-A1 | NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS | University of Copenhagen (DK) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024115641-A1 | NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS | UNIVERSITY OF COPENHAGEN (DK) | 2024-06-06 | — | — | WO | disclosed |