Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC12A2 | P55011 | 1/20 | 0.54 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283634 | 0.86 | SLC12A2 (0.56) | SLC12A2SLC12A5GAAPOLBALOX12 | |
| SCHEMBL283635 | 0.86 | SLC12A2 (0.56) | SLC12A2SLC12A5GAAPOLBALOX12 | |
| SCHEMBL2306082 | 0.86 | SLC12A2 (0.56) | SLC12A2SLC12A5GAAPOLBALOX12 | |
| SCHEMBL2929267 | 0.83 | SLC12A2 (0.54) | SLC12A2SLC12A5GAAPOLBALOX12 | |
| SCHEMBL1691084 | 0.82 | SLC12A2 (0.52) | SLC12A2SLC12A5GAAPOLBALOX12 | |
| SCHEMBL1691225 | 0.82 | SLC12A2 (0.52) | SLC12A2SLC12A5GAAPOLBALOX12 | |
| SCHEMBL284269 | 0.82 | SLC12A2 (0.52) | SLC12A2SLC12A5GAAPOLBALOX12 | |
| SCHEMBL14239450 | 0.80 | SLC12A2 (0.50) | SLC12A2SLC12A5GAAPOLBALOX12 | |
| SCHEMBL19285370 | 0.78 | SLC12A2 (0.47) | SLC12A2SLC12A5GAAPOLBALOX12 | |
| SCHEMBL19285120 | 0.78 | SLC12A2 (0.47) | SLC12A2SLC12A5GAAPOLBALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140968-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD AND USE THEREFOR | 广州市联瑞制药有限公司 | 2024-07-04 | — | — | WO | disclosed |