SCHEMBL284269

SCHEMBL284269

Cc1ccc(S(=O)(=O)OCC2CCCCO2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC12A2 P55011 1/20 0.52
SLC12A5 Q9H2X9 1/20 0.52
GAA P10253 2/20 0.46
POLB P06746 2/20 0.46
ALOX12 P18054 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 2/20 0.44
LMNA P02545 2/20 0.44
NPC1 O15118 1/20 0.44
KDM4E B2RXH2 1/20 0.43
HPGD P15428 2/20 0.42
RCE1 Q9Y256 1/20 0.42
CXCR4 P61073 1/20 0.42
ALDH1A1 P00352 5/20 0.42
NR2F2 P24468 1/20 0.42
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1691225 1.00 SLC12A2 (0.52) SLC12A2SLC12A5GAAPOLBALOX12
SCHEMBL1691084 1.00 SLC12A2 (0.52) SLC12A2SLC12A5GAAPOLBALOX12
SCHEMBL2306082 0.96 SLC12A2 (0.56) SLC12A2SLC12A5GAAPOLBALOX12
SCHEMBL283634 0.96 SLC12A2 (0.56) SLC12A2SLC12A5GAAPOLBALOX12
SCHEMBL283635 0.96 SLC12A2 (0.56) SLC12A2SLC12A5GAAPOLBALOX12
SCHEMBL19285120 0.91 SLC12A2 (0.47) SLC12A2SLC12A5GAAPOLBALOX12
SCHEMBL19285370 0.91 SLC12A2 (0.47) SLC12A2SLC12A5GAAPOLBALOX12
SCHEMBL283511 0.91 SLC12A2 (0.47) SLC12A2SLC12A5GAAPOLBALOX12
SCHEMBL14239450 0.86 SLC12A2 (0.50) SLC12A2SLC12A5GAAPOLBALOX12
SCHEMBL3609709 0.86 ALDH1A1 (0.42) POLBMEN1KMT2ASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183219-A1 CONDENSED SUBSTITUTED HYDROPYRROLES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY 2023-06-15 US claimed
US-20230150986-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 UNITED STATES GOVERNMENT 2023-05-18 US claimed
US-20230122344-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 UNITED STATES GOVERNMENT 2023-04-20 US claimed
EP-4139303-A1 CONDENSED SUBSTITUTED HYDROPYRROLES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 Vanderbilt University (US) 2023-03-01 EP claimed
WO-2021216951-A1 CONDENSED SUBSTITUTED HYDROPYRROLES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY (US) 2021-10-28 WO claimed
WO-2021119254-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY (US) 2021-06-17 WO claimed
WO-2021119265-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY (US) 2021-06-17 WO claimed
US-12617777-B2 GPR84 antagonists and uses thereof Liminal Biosciences Limited (GB) 2026-05-05 US disclosed
US-20260028356-A1 1,3,4,7-TETRAHYDRO-2H-PYRROLO[3',2':5,6]PYRIDO[2,3-B][1,4]OXAZEPINE BCL-2 INHIBITORS ABBVIE INC (US) 2026-01-29 US disclosed
US-20250066388-A1 1,3,4,7-TETRAHYDRO-2H-PYRROLO[3',2':5,6]PYRIDO[2,3-B][1,4]OXAZEPINE BCL-2 INHIBITORS ABBVIE INC (US) 2025-02-27 US disclosed
WO-2024218296-A1 COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF LEUCINE-RICH REPEAT KINASE 2 (LRRK2) INHIBITORS H. LUNDBECK A/S (DK) 2024-10-24 WO disclosed
EP-4422750-A1 LRRK2 INHIBITORS H. Lundbeck A/S (DK) 2024-09-04 EP disclosed
EP-3604305-B1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMA CO LTD (JP) 2024-08-28 EP disclosed
US-20080194549-A1 Organic Compounds NOVARTIS AG (CH) 2008-08-14 US disclosed
EP-1863477-A1 3,4-SUBSTITUTED PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF HYPERTENSION Novartis AG (CH) 2007-12-12 EP disclosed
WO-2006100036-A1 3, 4-SUBSTITUTED PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF HYPERTENSION NOVARTIS AG (CH) 2006-09-28 WO disclosed
EP-0785933-A1 INDOLE DERIVATIVES AS 5HT1-LIKE AGONISTS Pfizer Limited (GB) 1997-07-30 EP disclosed
WO-1996011195-A1 INDOLE DERIVATIVES AS 5HT1-LIKE AGONISTS PFIZER LIMITED (GB) 1996-04-18 WO disclosed
US-4606753-A PLANT GROWTH REGULATORS SHELL OIL COMPANY (US) 1986-08-19 US disclosed
US-4588821-A 2-oxabicyclo[2.2.1]heptan-6-ol ether herbicides SHELL OIL COMPANY (US) 1986-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028356-A1 1,3,4,7-TETRAHYDRO-2H-PYRROLO[3',2':5,6]PYRIDO[2,3-B][1,4]OXAZEPINE BCL-2 INHIBITORS BCL9L, BCL2L2, BCL2L1 SLC12A2 436/4885SLC12A5 732/4885GAA 4803/4885
US-20230183219-A1 CONDENSED SUBSTITUTED HYDROPYRROLES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 CHRM3, CHRM2, CHRM4 SLC12A2 3490/4885SLC12A5 3461/4885GAA 3428/4885
US-20250066388-A1 1,3,4,7-TETRAHYDRO-2H-PYRROLO[3',2':5,6]PYRIDO[2,3-B][1,4]OXAZEPINE BCL-2 INHIBITORS BCL9L, BCL2L1, BCL2L2 SLC12A2 1814/4885SLC12A5 1957/4885GAA 4169/4885
US-12617777-B2 GPR84 antagonists and uses thereof GPR84, GPR88, GPR3 SLC12A2 972/4885SLC12A5 1175/4885GAA 4713/4885
US-20080194549-A1 Organic Compounds REN, ACE, OTC SLC12A2 3030/4885SLC12A5 2444/4885GAA 118/4885
US-20230122344-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 CHRM2, CHRM3, CHRM4 SLC12A2 4238/4885SLC12A5 4008/4885GAA 2596/4885
US-20230150986-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 CHRM3, CHRM2, CHRM4 SLC12A2 3894/4885SLC12A5 3708/4885GAA 2818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.