Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474185 | 0.83 | CYP2A6 (0.44) | HTR2AHTR2CHTR2BTP53HTR1A | |
| SCHEMBL992833 | 0.83 | CYP2A6 (0.44) | HTR2AHTR2CHTR2BTP53HTR1A | |
| SCHEMBL4392149 | 0.81 | TAAR1 (0.50) | HTR2AHTR2CHTR2BTP53HTR1A | |
| Hydrochloric Acid SCHEMBL5957928 | 0.81 | HTR2A (0.46) | HTR2AHTR2CHTR2BTP53HTR1A | |
| Hydrochloric Acid SCHEMBL16401793 | 0.79 | TAAR1 (0.48) | HTR2AHTR2CHTR2BTP53HTR1A | |
| SCHEMBL30970531 | 0.79 | HTR2A (0.40) | HTR2AHTR2CHTR2BTP53HTR1A | |
| SCHEMBL4604208 | 0.78 | KMT2A (0.48) | HTR2ATP53HTR1AHTR7HTR6 | |
| SCHEMBL6194409 | 0.78 | CHEK1 (0.41) | HTR2AHTR2CHTR2BTP53HTR1A | |
| Hydrochloric Acid SCHEMBL30603519 | 0.77 | IDO1 (0.57) | HTR2AHTR2CHTR2BHTR1ATRPM8 | |
| Hydrochloric Acid SCHEMBL4933843 | 0.76 | HTR2A (0.42) | HTR2AHTR2CHTR2BTP53HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140968-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD AND USE THEREFOR | 广州市联瑞制药有限公司 | 2024-07-04 | — | — | WO | disclosed |