Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971034 | 0.87 | PKMYT1 (0.36) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL27388209 | 0.87 | PKMYT1 (0.36) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL30971076 | 0.86 | DYRK1A (0.39) | DYRK1AMEN1KMT2AIKBKBALDH1A1 | |
| SCHEMBL27388782 | 0.84 | DYRK1A (0.43) | DYRK1AMEN1KMT2AIKBKBALDH1A1 | |
| SCHEMBL30971170 | 0.84 | DYRK1A (0.43) | DYRK1AMEN1KMT2AIKBKBALDH1A1 | |
| SCHEMBL30971130 | 0.78 | IKBKB (0.40) | DYRK1AIKBKBALDH1A1KDM4EHPGD | |
| SCHEMBL30971074 | 0.76 | DYRK1A (0.43) | DYRK1AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27388857 | 0.76 | DYRK1A (0.43) | DYRK1AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30971168 | 0.75 | PKMYT1 (0.39) | MEN1KMT2AIKBKBPDE4APDE4B | |
| SCHEMBL27388280 | 0.75 | PKMYT1 (0.39) | MEN1KMT2AIKBKBPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |