Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388285 | 0.86 | BTK (0.39) | IKBKBPIK3CALCKBTKPKMYT1 | |
| SCHEMBL30971232 | 0.86 | BTK (0.39) | IKBKBPIK3CALCKBTKPKMYT1 | |
| SCHEMBL30971076 | 0.80 | DYRK1A (0.39) | IKBKBLMNAPKMYT1DYRK1AALDH1A1 | |
| SCHEMBL30971083 | 0.78 | DYRK1A (0.44) | IKBKBLMNAPKMYT1DYRK1AALDH1A1 | |
| SCHEMBL27402009 | 0.77 | GRM2 (0.43) | IKBKBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL30905535 | 0.77 | GRM2 (0.43) | IKBKBALDH1A1KDM4EGAAHPGD | |
| SCHEMBL30971170 | 0.75 | DYRK1A (0.43) | IKBKBLMNAPKMYT1DYRK1AALDH1A1 | |
| SCHEMBL27388782 | 0.75 | DYRK1A (0.43) | IKBKBLMNAPKMYT1DYRK1AALDH1A1 | |
| SCHEMBL30905596 | 0.73 | IKBKB (0.42) | IKBKBLMNALCKBTKPKMYT1 | |
| SCHEMBL27401511 | 0.73 | IKBKB (0.42) | IKBKBLMNALCKBTKPKMYT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |