Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971165 | 0.88 | GRM2 (0.41) | GRM2PKMYT1MEN1KMT2A | |
| SCHEMBL27388051 | 0.88 | GRM2 (0.41) | GRM2PKMYT1MEN1KMT2A | |
| SCHEMBL30971091 | 0.86 | GRM2 (0.37) | GRM2SMN1; SMN2EIF2AK3XDHKDM4E | |
| SCHEMBL30971263 | 0.85 | GRM2 (0.37) | DYRK1AGRM2EIF2AK3ALDH1A1SCN9A | |
| SCHEMBL30971170 | 0.81 | DYRK1A (0.43) | DYRK1ASMN1; SMN2EIF2AK3ALDH1A1PARP1 | |
| SCHEMBL27388782 | 0.81 | DYRK1A (0.43) | DYRK1ASMN1; SMN2EIF2AK3ALDH1A1PARP1 | |
| SCHEMBL30971301 | 0.78 | GRM2 (0.39) | DYRK1AGRM2ALDH1A1SCN9AKDM4E | |
| SCHEMBL30971066 | 0.78 | PKMYT1 (0.39) | GRM2PKMYT1MEN1KMT2A | |
| SCHEMBL27387968 | 0.78 | PKMYT1 (0.39) | GRM2PKMYT1MEN1KMT2A | |
| SCHEMBL30971074 | 0.76 | DYRK1A (0.43) | DYRK1ASMN1; SMN2EIF2AK3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |