Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30971070 | 0.84 | GRM2 (0.39) | GRM2HSD17B10GAAHPGD | |
| SCHEMBL30971263 | 0.81 | GRM2 (0.37) | GRM2DYRK1APIM2HSD17B10ALDH1A1 | |
| SCHEMBL30971180 | 0.78 | DYRK1A (0.43) | GRM2DYRK1AALDH1A1KDM4ENPSR1 | |
| SCHEMBL30971261 | 0.77 | DYRK1A (0.44) | DYRK1AHSD17B10CD274ALDH1A1KDM4E | |
| SCHEMBL30905524 | 0.74 | PARP1 (0.39) | GRM2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL27397852 | 0.74 | PARP1 (0.39) | GRM2HSD17B10ALDH1A1KMT2A | |
| SCHEMBL30971117 | 0.74 | PKMYT1 (0.42) | GRM2 | |
| SCHEMBL27387964 | 0.74 | PKMYT1 (0.42) | GRM2 | |
| SCHEMBL20674243 | 0.72 | LCK (0.41) | GRM2DYRK1APRKD3CLK2PRKD2 | |
| SCHEMBL30971335 | 0.72 | GRM2 (0.38) | GRM2ALDH1A1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |