Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PGK1 | P00558 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882909 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1LMNACHRNB2CHRNA4 | |
| SCHEMBL30971085 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1LMNACHRNB2CHRNA4 | |
| SCHEMBL26661686 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1LMNAPGK1CHRNB2 | |
| SCHEMBL31735888 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1LMNACHRNB2CHRNA4 | |
| SCHEMBL13916682 | 0.74 | KDM4E (0.69) | KDM4EALDH1A1LMNACHRNB2CHRNA4 | |
| SCHEMBL26790682 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1LMNAPGK1CHRNB2 | |
| SCHEMBL13916685 | 0.72 | KDM4E (0.67) | KDM4EALDH1A1LMNACHRNB2CHRNA4 | |
| SCHEMBL6492005 | 0.72 | KDM4E (0.49) | KDM4EALDH1A1LMNACHRNB2CHRNA4 | |
| SCHEMBL24463160 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1LMNACHRNB2CHRNA4 | |
| SCHEMBL30390474 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1LMNACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638420-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | Exelixis, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137671-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |