Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.86 |
| ▸ | PGR | P06401 | 5/20 | 0.86 |
| ▸ | AR | P10275 | 5/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.86 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.86 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.86 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.86 |
| ▸ | CNR1 | P21554 | 1/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233669 | 0.94 | NR3C1 (0.88) | NR3C1PGRARCYP3A4NR3C2 | |
| SCHEMBL31697459 | 0.94 | NR3C1 (0.88) | NR3C1PGRARCYP3A4NR3C2 | |
| Fluticasone Propionate SCHEMBL9363101 | 0.92 | NR3C1 (0.97) | NR3C1PGRARCYP3A4NR3C2 | |
| Fluticasone Propionate SCHEMBL9363108 | 0.92 | NR3C1 (0.97) | NR3C1PGRARCYP3A4NR3C2 | |
| Fluticasone Propionate SCHEMBL14343427 | 0.92 | NR3C1 (1.00) | NR3C1PGRARCYP3A4NR3C2 | |
| Fluticasone Propionate SCHEMBL416179 | 0.92 | NR3C1 (1.00) | NR3C1PGRARCYP3A4NR3C2 | |
| Fluticasone Propionate SCHEMBL191134 | 0.92 | NR3C1 (1.00) | NR3C1PGRARCYP3A4NR3C2 | |
| Fluticasone Propionate SCHEMBL13026160 | 0.92 | NR3C1 (1.00) | NR3C1PGRARCYP3A4NR3C2 | |
| Fluticasone Propionate SCHEMBL15944858 | 0.92 | NR3C1 (1.00) | NR3C1PGRARCYP3A4NR3C2 | |
| Fluticasone Propionate SCHEMBL4283 | 0.92 | NR3C1 (1.00) | NR3C1PGRARCYP3A4NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631952-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND CONJUGATE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024149093-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND CONJUGATE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-07-18 | — | — | WO | disclosed |