Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 3/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14123951 | 0.88 | KMT2A (0.53) | KMT2ATLR2CASP3ALDH1A1MDM2 | |
| SCHEMBL16093051 | 0.87 | KMT2A (0.50) | KMT2ATLR2CASP3ALDH1A1MDM2 | |
| SCHEMBL10078346 | 0.87 | KMT2A (0.50) | KMT2ATLR2CASP3ALDH1A1MDM2 | |
| SCHEMBL29400961 | 0.87 | KMT2A (0.57) | KMT2ATLR2MDM2 | |
| SCHEMBL21462054 | 0.87 | KMT2A (0.57) | KMT2ATLR2MDM2 | |
| SCHEMBL25358347 | 0.87 | KMT2A (0.57) | KMT2ATLR2MDM2 | |
| SCHEMBL29958970 | 0.87 | KMT2A (0.57) | KMT2ATLR2MDM2 | |
| SCHEMBL178771 | 0.87 | KMT2A (0.57) | KMT2ATLR2MDM2 | |
| SCHEMBL29391986 | 0.87 | KMT2A (0.57) | KMT2ATLR2MDM2 | |
| SCHEMBL29401249 | 0.87 | KMT2A (0.57) | KMT2ATLR2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024149093-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND CONJUGATE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2024-07-18 | — | — | WO | disclosed |