SCHEMBL10078346

SCHEMBL10078346

C=CCOC(=O)NCCC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)NC

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.50
▸ TLR2 O60603 2/20 0.46
▸ MDM2 Q00987 2/20 0.42
▸ CASP3 P42574 1/20 0.42
▸ CASP1 P29466 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16093051 1.00 KMT2A (0.50) KMT2ATLR2MDM2CASP3CASP1
SCHEMBL29400732 0.90 KMT2A (0.55) KMT2ATLR2MDM2CASP3CASP1
SCHEMBL29400312 0.90 KMT2A (0.55) KMT2ATLR2MDM2CASP3CASP1
SCHEMBL12898821 0.90 KMT2A (0.55) KMT2ATLR2MDM2CASP3CASP1
SCHEMBL178688 0.90 KMT2A (0.55) KMT2ATLR2MDM2CASP3CASP1
SCHEMBL119653 0.90 KMT2A (0.55) KMT2ATLR2MDM2CASP3CASP1
SCHEMBL119648 0.90 KMT2A (0.55) KMT2ATLR2MDM2CASP3CASP1
SCHEMBL13938802 0.89 KMT2A (0.59) KMT2ATLR2MDM2
SCHEMBL14123951 0.88 KMT2A (0.53) KMT2ATLR2MDM2CASP3CASP1
SCHEMBL30972259 0.87 KMT2A (0.48) KMT2ATLR2MDM2CASP3CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150044693-A1 Levetiracetam Immunoassays ARK DIAGNOSTICS, INC. 2015-02-12 — — US disclosed
US-20120190047-A1 Levetiracetam Immunoassays ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT 2012-07-26 — — US disclosed
US-8168756-B2 Levetiracetam immunoassays ARK DIAGNOSTICS, INC. (US) 2012-05-01 — — US disclosed
US-20100173427-A1 LEVETIRACETAM IMMUNOASSAYS ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT 2010-07-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120190047-A1 Levetiracetam Immunoassays GABRG1, GABRA6, LY96 KMT2A 1674/4885TLR2 4281/4885MDM2 3125/4885
US-20100173427-A1 LEVETIRACETAM IMMUNOASSAYS GABRG1, GABRA6, LY96 KMT2A 1674/4885TLR2 4281/4885MDM2 3125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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