Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844292 | 0.92 | KDM1A (0.44) | RENKDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL5402328 | 0.92 | KDM1A (0.44) | RENKDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL5402299 | 0.92 | KDM1A (0.44) | RENKDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL30185737 | 0.90 | MAPK8 (0.46) | RENMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL30844263 | 0.87 | KDM1A (0.45) | RENKDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL29680012 | 0.87 | MAPK8 (0.48) | RENMAPK8MAPK9MAPK10KEAP1 | |
| SCHEMBL30008261 | 0.87 | NMT1 (0.44) | KDM1AMAOBKDM5AKDM1B | |
| SCHEMBL31720924 | 0.87 | PRCP (0.41) | RENKDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL29531541 | 0.87 | PRCP (0.41) | RENKDM1AMAPK8MAPK9MAPK10 | |
| SCHEMBL30686009 | 0.86 | MAPK8 (0.49) | RENMAPK8MAPK9MAPK10KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132726-A1 | SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE | UNIWERSYTET GDANSKI (PL) | 2024-06-27 | — | — | WO | disclosed |