Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 9/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844292 | 1.00 | KDM1A (0.44) | KDM1AGHSRRENMAOBKDM5A | |
| SCHEMBL5402328 | 1.00 | KDM1A (0.44) | KDM1AGHSRRENMAOBKDM5A | |
| SCHEMBL29531541 | 0.95 | PRCP (0.41) | KDM1ARENMAOBKDM5AKDM1B | |
| SCHEMBL31720924 | 0.95 | PRCP (0.41) | KDM1ARENMAOBKDM5AKDM1B | |
| SCHEMBL30844263 | 0.93 | KDM1A (0.45) | KDM1AGHSRRENMAOBKDM5A | |
| SCHEMBL31544483 | 0.92 | KDM1A (0.44) | KDM1AGHSRRENMAOBKDM5A | |
| SCHEMBL30974366 | 0.92 | REN (0.46) | KDM1ARENMAOBKDM5AKDM1B | |
| SCHEMBL9120793 | 0.91 | GHSR (0.41) | KDM1AGHSRRENCPB2 | |
| SCHEMBL31385440 | 0.91 | GHSR (0.41) | KDM1AGHSRRENCPB2 | |
| SCHEMBL29588633 | 0.91 | GHSR (0.41) | KDM1AGHSRRENCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217571-B1 | Gene therapy by small fragment homologous replacement | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-05-15 | — | — | US | disclosed |
| US-7189833-B2 | Prostate cancer gene | SERONO GENETICS INSTITUTE S.A. (FR) | 2007-03-13 | — | — | US | disclosed |
| US-7038011-B2 | Methods and tools for identifying compounds which modulate atherosclerosis by impacting LDL-proteoglycan binding | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-05-02 | — | — | US | disclosed |
| US-6933284-B2 | Methods and tools for identifying compounds which modulate atherosclerosis by impacting LDL-proteoglycan binding | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-08-23 | — | — | US | disclosed |
| EP-0636028-B1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING AN AMPHIPHATIC CATIONIC PEPTIDE | UNIV CALIFORNIA (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-0708637-B1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | UNIV CALIFORNIA (US) | 2004-01-28 | — | — | EP | disclosed |
| US-6579682-B1 | Low Density Lipoproteins (LDL); drug screening | THE REGENTS OF UNIVERSITY OF CALIFORNIA | 2003-06-17 | — | — | US | disclosed |
| EP-1052292-B1 | Prostate cancer gene | GENSET SA (FR) | 2003-04-09 | — | — | EP | disclosed |
| US-20020165345-A1 | Prostate cancer gene | SERONO GENETICS INSTITUTE S.A. (FR) | 2002-11-07 | — | — | US | disclosed |
| EP-1236473-A2 | Self-assembling polynucleotide delivery system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-0656747-A1 | COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-06-14 | — | — | EP | disclosed |
| WO-1995004064-A9 | POLYNUCLEOTIDE DECOYS THAT IHNIBIT MHC-II EXPRESSION AND USES THEREOF | — | 1995-03-09 | — | — | WO | disclosed |
| WO-1995004064-A1 | POLYNUCLEOTIDE DECOYS THAT IHNIBIT MHC-II EXPRESSION AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-02-09 | — | — | WO | disclosed |
| WO-1995003694-A1 | METHOD FOR MAKING UNIVERSAL DONOR CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-02-09 | — | — | WO | disclosed |
| EP-0636028-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1995002397-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-01-26 | — | — | WO | disclosed |
| EP-0626852-A1 | METHOD FOR MAKING UNIVERSAL DONOR CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-12-07 | — | — | EP | disclosed |
| WO-1994004032-A1 | COMPOSITION AND METHOD FOR ALTERING DNA SEQUENCES BY HOMOLOGOUS RECOMBINATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1993019768-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-10-14 | — | — | WO | disclosed |
| WO-1993014769-A1 | METHOD FOR MAKING UNIVERSAL DONOR CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-08-05 | — | — | WO | disclosed |