SCHEMBL30974583

SCHEMBL30974583

COC(=O)c1cc(Cl)ccc1Oc1cccc(-c2ccccc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
MRGPRX4 Q96LA9 1/20 0.47
ACLY P53396 3/20 0.47
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
PTGER2 P43116 1/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
LMNA P02545 2/20 0.45
NPSR1 Q6W5P4 1/20 0.44
ABL1 P00519 1/20 0.43
CNR1 P21554 1/20 0.43
SERPINE1 P05121 1/20 0.43
HTT P42858 1/20 0.43
NPC1 O15118 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29250438 1.00 PTGER4 (0.48) PTGER4SLC6A4SLC6A3TDP1MRGPRX4
SCHEMBL4450385 0.88 PTGER4 (0.56) PTGER4SLC6A4SLC6A3TDP1MRGPRX4
SCHEMBL4449372 0.85 KDM4E (0.59) PTGER4TDP1MRGPRX4KDM4EPOLB
SCHEMBL29250437 0.85 KDM4E (0.46) SLC6A4SLC6A3ACLYKDM4EPOLB
SCHEMBL21359489 0.85 POLB (0.49) SLC6A3KDM4EPOLBLMNANPSR1
SCHEMBL30974578 0.85 KDM4E (0.46) SLC6A4SLC6A3ACLYKDM4EPOLB
SCHEMBL30974620 0.84 L3MBTL1 (0.58) PTGER4SLC6A4SLC6A3TDP1MRGPRX4
SCHEMBL5362837 0.84 L3MBTL1 (0.58) PTGER4SLC6A4SLC6A3TDP1MRGPRX4
SCHEMBL29251268 0.84 CTNNB1 (0.51) PTGER4MRGPRX4KDM4EPOLBPTGER2
SCHEMBL30974617 0.84 CTNNB1 (0.51) PTGER4MRGPRX4KDM4EPOLBPTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084706-A Synthesis method of 2- (4-hydroxyphenoxy) benzamide compound 河北科技大学 2024-05-28 CN disclosed